Abstract: Objective The protection and inheritance of cultural heritage space have become an important part of territorial spatial planning. At present, the research on the construction of cultural heritage spatial protection system in the new era is still in the exploratory stage. This research explores the construction method of cultural heritage protection system, in order to provide reference for the protection and utilization of cultural heritage space in the context of territorial spatial planning.Methods Taking Tianjin as the research object, this research investigates the current status of the protection of historical and cultural heritage resources in Tianjin, summarizes the limitations of the original protection system in the new era, and researches the construction of a municipal cultural heritage space protection system by virtue of the geographic information system under the support of the theory of cultural heritage space.Results The research builds a general framework for heritage protection in Tianjin in the context of territorial spatial planning by identifying heritage values, forming protection zones, establishing a "point-line-plane" protection system, and implementing a management mechanism to secure the protection.Conclusion The research explores the construction method of cultural heritage protection system, and proposes the following four suggestions for the protection and utilization of cultural heritage space in the context of territorial spatial planning:Supplement the multi-dimensional value judgment; strengthen the holistic nature of heritage protection; play the leading role of culture leadership; and carry out dynamic supervision and control.