Abstract: The existing location-based campus environmental safety research mainly takes the objective case data as the research object, which fails to reveal the internal relationship between students' perceived safety and the environmental factors of a specific location. We conducted a location-based survey by using Maptionnaire among students in Guangzhou Higher Education Mega Center, and analyzed the level of perceived safety of students and their spatial distribution, in terms of campus traffic, accidents and crime. The findings showed that students indicated lower level of perceived safety. The most frequent markings of fearful places were mainly concentrated on green space, urban village and stadiums near campus, while students placed most of the markings with high perceived safety within the campus. After conducting the field investigation, we analyzed the environmental factors shaping perceived safety based on the principles of crime prevention through environmental design (CPTED), and proposed optimized environmental design strategies to improve perceived safety of students.