Abstract: Public health emergencies have become an important urban issue, arousing our further thinking on how to improve the quality of urban and rural living ecological environment construction. This paper reviews the close relationship between public health and urban spatial planning layout, discusses the concepts of “healthy city” and “resilient city” in the construction of human settlement environment, and puts forward four spatial planning strategies to deal with public health emergencies: 1) Building regional redundant space and resilience response based on the overall spatial evaluation of cities and regions; 2) Establishing an open space system with urban park green space, ventilation corridor and community public space as the core; 3) Laying out medical and health facilities rationally and strengthening public health emergency preparedness and planning; 4) Improving the information and data interaction platform to build a community-based emergency management model. This paper discusses the planning strategy system to deal with public health events from the three levels of region, city and community, and focuses on the planning and management at the community level, strengthening the system of community responsibility planners to build a healthy, safe and sustainable space environment together with community residents.