Abstract: Wuhan is one of the cities with the fastest urbanization development progress in the middle area of China. The green infrastructure that provides important ecosystem services is facing problems such as space replacement, total reduction, and structural fragmentation under the expansion of built areas. Starting from the stormwater regulation and storage function of green infrastructure, this paper analyzes the spatial patterns and hydrological locations of green infrastructure in Wuhan with data of topography, land use type, interpreted remote sensing images, etc. To simulate urban expansion, the paper calculates the transformation probability to construct a cellular automaton model by integrating the development guidance and spatial control constraints of the growth of built areas as operating rules. The pattern evolution and waterlogging risks of various green infrastructures caused by urban expansion are analyzed. It disclosed that the key hydrological locations in Wuhan are sensitive and easily occupied in urban expansion, and the built areas face the risk of waterlogging caused by the decline of the regulation and storage function. It is hard to avoid conflicts among different land uses in urban expansion. As a natural carrier of urban stormwater regulation and storage, green infrastructure plays a structural and fundamental role in the benign cycle of the urban hydrological processes. Protecting areas that are highly sensitive, easily occupied, and have key hydrological functions in urban development and establishing a multi-level control system according to the risk level assessed is of great significance for protecting the green infrastructure and preventing waterlogging in Wuhan.